Antecedents of Digital Twin Adoption for Precision Cancer Care in Urban India

India is the most populous country in the world, with a rising urban population and witnessing a surge in noncommunicable diseases such as cancer that impose significant pressure on healthcare professionals, hospitals, and city planners. Over the last decade, India has pursued a vision to transform urban areas into smart cities and roll out digital infrastructure. Rapid urbanization coupled with an ageing population has accelerated demand for precision cancer care (PCC) solutions using advanced technologies such as digital twins (DT), leveraging the developing digital infrastructure in urban India. The fast evolution of e-health technologies and digital infrastructure outstrips healthcare professional readiness, creating challenges for DT adoption for PCC. Past studies on DT adoption primarily focused on organizational adoption and technical implementation challenges. This study addresses this research gap by leveraging the Unified Theory of Acceptance and Use of Technology (UTAUT) framework to investigate the factors that influence the adoption intention of DT for PCC in urban India. The article reports actionable insights and implications for researchers, healthcare professionals, top management of hospitals, smart city planners, government agencies, and urban policymakers. The study will assist stakeholders such as cancer care organizations, technology service providers, and city planners in planning, designing, and implementing DT for PCC.