DOI: 10.2807/1560-7917.es.2026.31.24.2600477 ISSN: 1560-7917

Andes virus outbreak linked to expedition cruise ship travel, multi-country investigation and response, April to June 2026

Oda Everdina van den Berg, , Ettore Severi, Freddy Mutoka-Banza, Michele van Vugt, Esther M Schadd, María Cruz Calvo Reyes, Laura Santos Larrégola, Pedro Valdivia Prieto, François-Xavier Lescure, Mark A Cachia, Mayank Singal, Mirko Faber, Walter Zingg, Nazir Ahmed Ismail, Margreet JM te Wierik, Tjalling Leenstra, Chantal Reusken, Susan van den Hof,

As at 18 June 2026, 13 cases (12 confirmed and one probable) of Andes orthohantavirus have been reported (case–fatality: 23%), linked to the Dutch-flagged expedition cruise ship MV Hondius . The event involved individuals from 23 nationalities and required medical evacuation, repatriation, coordinated international contact tracing, isolation, quarantine and clinical and laboratory testing follow-up. To date, all cases have been passengers (10/121; 8%) or crew members (3/61; 5%). Ongoing monitoring and investigations aim to clarify the source of the outbreak, identify risk factors and prevent further spread.

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