DOI: 10.1039/d6ra07816h ISSN: 2046-2069
Analytical quality-by-design-assisted RP-HPLC method for simultaneous determination of cinnamaldehyde and chrysin in a lipid-based delivery system and its greenness assessment
Mohammed Arfath M I, Sushmitha, Verginia Stefhney Pinto, Amitha Shetty, Akhilesh Dubey, Namdev Dhas, Sri Renukadevi Balusamy, Manohar MahadevChou-Talalay analysis identified a 1 : 1 CN : CR ratio. RP-HPLC simultaneously quantified CN and CR, and SNEDDS optimisation resulted in rapid self-emulsification, nanosized droplets, and improved bioaccessibility.