Lipika Singhal, Swati Sharma, Ivneet Kour, Dipanshu Vasesi, Surinder Singhal, Varsha Gupta

AN INSIGHT INTO THE BACTERIAL ETIOLOGY AND ANTIMICROBIAL SUSCEPTIBILITY PATTERN OF BACTERIA CAUSING EAR INFECTIONS IN A TERTIARY CARE HOSPITAL IN NORTH INDIA.

  • General Medicine
  • General Earth and Planetary Sciences
  • General Environmental Science
  • General Medicine
  • Ocean Engineering
  • General Medicine
  • General Medicine
  • General Medicine
  • General Medicine
  • General Earth and Planetary Sciences
  • General Environmental Science
  • General Medicine

Background: Due to the inappropriate use of antibiotics along with poor compliance of the patients, resistance patterns have developed to commonly prescribed antibiotics for ear infections, especially in children. Otitis media, a common ear infection is one of the key contributors to antibiotic resistance. It is estimated that up to 40% of all preventable hearing impairments are caused by ear infections, leading to frequent antibiotic usage, especially in developing countries. Considering the upsurge in drug resistance, a study was conducted to provide an update on current bacteriological prole and antimicrobial susceptibility pattern as it would be useful for clinicians to start with the appropriate antibiotics at the earliest and to reduce the burden of emerging drug resistance especially during the ongoing Covid-19 pandemic. Material method: A retrospective study over a period of three years, starting from January 2018 to December 2020 in a tertiary care hospital where all ear discharge/ pus samples were processed. A total of 1050 ear discharge samples were cultured according to the standard microbiological procedures. Isolates were identied by conventional methods and antibiotic susceptibility proles were determined by standard disk diffusion method. All this data was then evaluated retrospectively. Data was analyzed by SPSS version 22 and the P value of less than 0.05 was considered as statistically signicant for the same. Results: Staphylococcus aureus and Pseudomonas aeruginosa were the most common microbes to be isolated. Gram positive cocci had high sensitivity to doxycycline and linezolid while Gram negative bacilli were sensitive to amikacin, imipenem, and piperacillin and tazobactam among the wide spectrum of antibiotics which were tested. These results indicate a rise in drug resistance in both Gram positive and Gram-negative microorganisms to many commonly prescribed antimicrobial agents by means of multiple drug resistance mechanisms. Conclusion: Patterns of sensitivity and resistance, help in proper selection of empiric therapy and prevention of emergence of resistant strains. Both culture and susceptibility tests have paramount importance for better management of ear infections, especially the drug-resistant ones.

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