Outline
DOI: 10.1039/d6ra05595h ISSN: 2046-2069
An activatable fluorescent probe for fibroblast activation protein α and its bioimaging applications
Lei Feng, Hengjing Chen, Zhenhao Tian, Wenpeng Li, Yifei Dang, Guobiao Liang, Chengjuan Xing, Xiaohong Shu, Jing Ning, Fangyu Yang, Xiaochi MaFibroblast activation protein α (FAP) is a promising therapeutic target. We designed fluorescent probe DDAF with high FAP selectivity and sensitivity. DDAF can facilitate the screening of FAP inhibitors and visualizes FAP in tumor cells and tissues.
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