DOI: 10.5863/1551-6776-28.8.747 ISSN: 2331-348X

Ampicillin-Sulbactam-Induced Liver Injury in a Pediatric Patient

Corey Fowler, Katie Namtu
  • Pharmacology (medical)
  • Pediatrics, Perinatology and Child Health

Drug-induced liver injury (DILI) is a rare adverse drug reaction (ADR) in pediatric patients and limited reports exist examining ampicillin-sulbactam-induced liver injury. This report summarizes a 12-year-old male who received ampicillin-sulbactam and subsequently developed liver injury characterized by elevated serum aminotransferases and bilirubin. Ampicillin-sulbactam was subsequently discontinued and the patient’s liver function tests (LFTs) rapidly improved. This report describes the rare adverse reaction of ampicillin-sulbactam-induced liver injury.

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