DOI: 10.1039/d6tb01685e ISSN: 2050-750X
Aligned PCL conduits integrated with tranilast-loaded GelMA hydrogel for immune-regulated peripheral nerve regeneration
Jun-kuan Shan, Jia-qi Fang, Xue-Han Jin, Bo Xu, Li-ping Nan, Zhi-jie Weng, Shu-hao Liu, Xin-hui Wu, Zhong Wu, Jun-jian LiuAligned PCL topographical guidance and tranilast-loaded GelMA-mediated immune regulation synergistically promote Schwann cell organization, macrophage phenotype remodeling, axonal regeneration, and remyelination.