Aerobic Exercise, Depression, Purpose in Life, and Quality of Life in Older Adults: Implications for Healthy Aging

Population aging has increased the importance of identifying modifiable lifestyle factors that promote psychological well-being and support brain health in later life. Aerobic exercise has consistently been associated with positive mental health outcomes; however, further evidence is needed regarding its relationship with depressive symptoms, purpose in life, and quality of life among community-dwelling older adults. The present study aimed to investigate the associations between aerobic exercise, depression, purpose in life, and quality of life in older adulthood, as well as their implications for healthy aging and brain health. A cross-sectional quantitative design was employed involving 151 older adults aged 65 years and older. Participants were recruited from Open Care Centers for the Elderly (KAPI) in the Municipality of Corinth, Greece, and through home visits in nearby communities. Data collection was conducted using the Purpose in Life Questionnaire–Short Form (PIL-SF), the Geriatric Depression Scale–Short Form (GDS-SF), and the WHOQOL-OLD Brief Form. Statistical analyses were performed using IBM SPSS Statistics, while non-parametric analyses were applied due to deviations from normality. The findings demonstrated that a higher frequency of aerobic exercise was significantly associated with lower depressive symptomatology, higher levels of purpose in life, and better quality of life. Participants who exercised almost daily reported significantly fewer depressive symptoms compared with those who exercised rarely or not at all. Furthermore, depressive symptoms were negatively correlated with both purpose in life and quality of life, whereas purpose in life was positively associated with quality of life. Gender differences were also observed, suggesting that the relationship between exercise and depressive symptoms may vary between men and women. Overall, the findings suggest that regular aerobic exercise may represent an important protective lifestyle factor associated with emotional well-being, psychological resilience, quality of life, and healthy aging among older adults. The study further supports the role of physical activity as a potentially beneficial non-pharmacological strategy for promoting mental health and supporting brain health in later life.