DOI: 10.1249/mss.0000000000003682 ISSN: 1530-0315

Advanced Footwear Technology, but not Acute Ingestion of a Ketone Monoester, Improves Running Economy in Middle- and Long-Distance Runners

Aidan J. Brady, Megan B. Moynagh, Simon Devenney, Brendan Egan

ABSTRACT

Purpose

This study examined the separate and combined effects of advanced footwear technology (AFT) and acute ingestion of a ketone monoester on running economy (RE), time-to-exhaustion (TTE), and other metabolic and cardiorespiratory parameters.

Methods

In a four-condition, placebo-controlled, randomized crossover design, 18 middle- and long-distance runners (male/female, 10/8, V̇O2peak: 59.4 ± 7.2 mL·kg-1·min-1) completed five 8 min stages of submaximal running (male: 10–14 km·h-1; female: 9–13 km·h-1) on a motorized treadmill, immediately followed by a ramp test to volitional exhaustion. Participants consumed 500 mL of either a 10% carbohydrate solution (CHO) or 500 mg·kg-1 body mass of an (R)-3-hydroxybutyl (R)-3-hydroxybutyrate ketone monoester with flavored water (KME) 20 min before exercise, and an additional 300 mL of the 10% carbohydrate solution or 250 mg·kg-1 body mass of KME during exercise, while wearing either Nike Pegasus Turbo (PEG) or Nike ZoomX Vaporfly Next% 3 (VAP) running shoes. The four randomized conditions were PEG+CHO, PEG+KME, VAP + CHO, and VAP + KME.

Results

RE was significantly improved during the third and fourth submaximal running stages in VAP + CHO and VAP + KME compared to PEG+CHO and PEG+KME (all P < 0.05; ES = 0.53-0.84). RE was also improved during the fifth submaximal running stage in VAP + KME compared to PEG+CHO, and in VAP + CHO and VAP + KME compared to PEG+KME (all P < 0.05; ES = 0.56-0.66). No differences in RE were found between CHO and KME conditions. TTE was significantly longer in VAP + CHO (381 ± 125 s) than PEG+CHO (356 ± 140 s; ES = 0.18, P = 0.023) and PEG+KME (329 ± 131 s, ES = 0.40, P < 0.001) and in VAP + KME (375 ± 125 s) than PEG+KME (ES = 0.35, P < 0.001).

Conclusions

AFT, but not the acute ingestion of a ketone monoester, improved the RE of trained male and female middle- and long-distance runners at submaximal running speeds.

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