ACUTE MYELOID LEUKEMIA PRESENTING WITH ACUTE THROMBOSIS OF THE PORTAL VEIN, SUPERIOR MESENTERIC VEIN, AND SPLENIC INFARCT: A CASE REPORT
Sunil Kumar Shivarame Gowda, Fekri Eltahir Abdalla, Raghunanda Narasimhaiah- Applied Mathematics
- General Mathematics
- General Medicine
- General Chemistry
- Pulmonary and Respiratory Medicine
- Pediatrics, Perinatology, and Child Health
- Microbiology
- Immunology
- General Medicine
- General Medicine
- Pharmacology (medical)
- General Medicine
- General Medicine
Background: Acute myeloid leukemia (AML) is a rapidly progressing cancer affecting the myeloid cells. The most common risk factor for AMLis the presence of an antecedent hematologic disorder, the most common of which is myelodysplastic syndrome (MDS). Some congenital disorders that predispose to AMLinclude Bloom syndrome, Down syndrome, congenital neutropenia, Fanconi anemia, and neurobromatosis. Persons who smoke tobacco have a small but statistically signicant (odds ratio:1.5) increased risk of developing AML. In several studies, the risk of AML was slightly increased in people who smoked compared to those who did not. Exposure to soot, creosote, inks, dyes, tanning solutions, and coal dust have also been associated with AML.[1] Thrombosis is a common complication in patients with acute leukemia. The clinical outcome of thrombosis in adult patients with acute myeloid leukemia (AML) is scarce. This case report demonstrates acute myeloid leukaemia causing acute thrombosis of the portal vein, superior mesenteric vein, and splenic infarct in a chronic smoker but an otherwise healthy person.