DOI: 10.38053/acmj.2010516 ISSN: 2718-0115

Acute kidney injury in intensive care unit patients: incidence, risk factors and mortality in a single-center retrospective cohort

Mustafa Gökhan Bayram, Dinçer Fırat Şeker
Show PDF Cite
Aims: Data on acute kidney injury (AKI) from state hospital intensive care units (ICUs) are limited. We determined the frequency of AKI over the ICU stay, the factors associated with it and its relationship with mortality using the risk, injury, failure, loss, end stage kidney disease (RIFLE) criteria.Methods: Adults with complete data staying at least 24 hours in a state hospital ICU between January 2022 and January 2025 were reviewed retrospectively; only index admissions were analyzed, each assigned the worst RIFLE class reached. Loss and End-stage classes, defined by dialysis dependence duration, were excluded. AKI already present at admission was counted together with AKI arising later, and exposures were recorded at any point during the stay, so the proportion reported is a period frequency of mixed prevalent and incident disease and the temporal sequence between exposure and renal injury could not be established. Because mechanical ventilation and vasopressor support were used in almost every patient who died, organ support could not serve as a covariate in the mortality model and is reported descriptively.Results: Of 890 patients (median age 76 years), 521 (58.5%) had AKI: risk 205 (23.0%), injury 141 (15.8%), failure 175 (19.7%). ICU mortality rose stepwise: 18.4%, 34.6%, 63.8% and 80.0% (p for trend

More from our Archive