DOI: 10.3390/jcm13010199 ISSN: 2077-0383

Acute Kidney Injury and Hepatorenal Syndrome in Patients with Cirrhosis

Nazli Begum Ozturk, Ece Janet Dinc, Abhishek Swami, Ahmet Gurakar
  • General Medicine

Acute kidney injury (AKI) is common in hospitalized patients with cirrhosis. Hepatorenal syndrome (HRS) is a type of AKI known as HRS-AKI. It is a severe complication of cirrhosis with high morbidity and mortality. While certain vasoconstrictor medications have been shown to improve HRS-AKI, no clear transplant-free survival benefit has been reported with medical therapies. Patients with HRS-AKI should be considered for urgent liver transplantation evaluation. In this review, we discuss the most recent updates on the definition, diagnosis, and management of AKI in cirrhosis, with special a emphasis on HRS.

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