DOI: 10.1002/anie.202318750 ISSN: 1433-7851

Acid‐Base Cascades in Zeotype Single Crystal for Sugar Conversion

Pengyao Sun, Haiyong Wang, He Wang, Wenmeng Ling, Yong Liu, Wenguang Zhou, Yuhe Liao, Liang Wang, Yue Lin, Chenguang Wang
  • General Chemistry
  • Catalysis


The chemically catalyzed production of fructose syrup from high concentrations of glucose is crucial for the food industry and biorefining. In this work, a single crystal catalyst was synthesized via protective desilication of zeolite while incorporating indium. Glucose was isomerized in methanol at concentrations as high as 33 wt % before being hydrolyzed with water. The final fructose production was 54.9 %, with 89.1 % selectivity and 93.3 % sugar recovery, the highest isomerization rate at the highest concentration ever reported. Indium was present in the single‐crystal catalyst as oxide nanoparticles and boundary framework atoms, and it achieved intelligent cooperation in the production of fructose syrup in methanol by catalyzing isomerization and selective glycosidation, minimizing degradation due to fructose accumulation and eliminating side reactions. This study contributed to the advancement of the industrial practice of chemically catalyzed glucose isomerization.

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