Abstract 17079: Relationship Between Neighborhood Level Deprivation and Cardiovascular Health Status Among 122,177 Adolescents, Analysis of PEDSnet Data

Introduction: Preservation of cardiovascular health (CVH) across the lifespan is essential to reducing cardiovascular disease burden. Greater knowledge of the relationship between neighborhood level deprivation and CVH in youth is needed.

Hypothesis: We hypothesized that worse socio/environmental deprivation is associated with poor/intermediate CVH status in adolescents.

Methods: Data from 2009-2019 were extracted from PEDSnet (a PCORI-funded network of pediatric health data). We modeled the relationship between CVH and neighborhood deprivation. National Area Deprivation Index values (ADI; scaled 1-100) were coded into PEDSnet and divided into tertiles (ADI<25=best, 25-52,

52=worst) for analysis. CVH status was scored from a subset of available AHA Life’s Essential 8 (LE8) scores including blood pressure, blood glucose, blood cholesterol, body mass index, smoking/tobacco exposure, and sleep. Overall CVH scores were derived as the average of the sum of the individual scores. Univariate and multivariate analyses were performed. SAS 9.4 was used ( p<0.05) .

Results: Data from 122,177 youth, 13-17 years old were analyzed. 51% were female, 24% lived in neighborhoods with ADI <25; 35% lived in neighborhoods with ADI

52. 58% were non-Hispanic white and 22% non-Hispanic Black. According to a multivariate logistic model, ADI 52 was associated with a 48% greater odds of poor/intermediate CVH status compared to ADI <25 (Figure). Female sex, ethnic-race categories of Non-Hispanic White and Other, as well private or other forms of non-public insurance coverage were associated with a lower odds of intermediate/poor CVH (Table). Interaction terms for age, ADI, race and ethnicity were not significant.

Conclusions: Higher neighborhood deprivation is associated with poor/intermediate CVH status. We recommend greater attention to preserving CVH status within high deprivation communities to preserve and promote CVH status across the lifespan.