Abstract 14794: Relationship Between Cerebral Infarction Incidence and Humidity in a Super-Aging Society
Kihei Yoneyama, Shunichi Doi, Toshiya Yoshida, Yasuhito Kawagoe, Yuki Ishibashi, Masaki Izumo, Yasuhiro Tanabe, Tomoo Harada, Yoshihiro J Akashi- Physiology (medical)
- Cardiology and Cardiovascular Medicine
Introduction: Cerebral infarction is one of the major causes of physical disability among the elderly worldwide. Weather temperature and humidity are rarely reported as predictors of cerebral infarction in our super-aging society.
Hypothesis: Temperature and humidity are associate with cerebral infarction admission in super aging society.
Methods: The Japanese registry of all cardiac and vascular diseases database includes patients with cardio-cerebrovascular disease who required admission and constitutes a nationwide dataset in Japan. This study included 606,807 consecutive patients with cerebrovascular disease requiring admission were admitted between 2015 and 2019. We investigated the relationship between cerebral infarction admission and temperature, or humidity.
Results: Data were collected from 422,759 admitted patients with cerebral infarction. In the population with cerebrovascular disease admission, the median age was 75.0 (66.0-83.0) years and 55.8% of subjects were male. The mean temperature and humidity 1 day before cerebral infarction hospitalization were 17.2 °C and 69%, respectively. Multilevel mixed-effects linear regression models showed non-linear relationship of temperature and humidity with cerebral infarction admissions after adjusting for air pollution, hospital, and patient demographics. A negative linear association was found between mean temperature and humidity with cerebral infarction admission at mean temperature <7°C and mean humidity <40% (coefficient, -2.098 [-2.220 to -1.976] per °C, coefficient, 0.165 [0.151 to 0.179] per %, respectively).However, a positive linear association was found at mean temperature ≥7°C, at mean humidity ≥40% (coefficient, 0.190 [0.161 to 0.219]per °C, coefficient, 0.136 [0.103 to 0.168] per %, respectively).
Conclusions: Extremely lower or higher temperature and humidity are both associated with an increased incidence of cerebral infarction admission in Japan.