Abstract 14769: Peripheral Venous Pressure Measured With a Novel Miniature Pressure Transducer Correlates With Central Venous Pressure in Heart Failure, Heart Transplant, and Left Ventricular Assist Device Patients
Sarah Flint, Aaron Wengrofsky, Peter P Vlismas, Elliot Wiesenfeld, Yogita M Rochlani, Patricia chavez, Sasha Vukelic, Sandhya Murthy, Shivank Madan, Omar Saeed, Snehal R Patel, Jooyoung Shin, Ulrich P Jorde, Daniel B Sims- Physiology (medical)
- Cardiology and Cardiovascular Medicine
Introduction: Peripheral venous pressure (PVP) has been shown to accurately correlate with central venous pressure (CVP) when measured using a conventional manometer and pressure tubing. We investigated the correlation between PVP as measured by a novel pressure transducer and CVP in heart failure (HF), heart transplant (HTx), and left ventricular assist device (LVAD) patients.
Methods: A prospective, cross-sectional study examining PVP from February 2022 to May 2023 was conducted. The analysis was limited to patients undergoing right heart catheterization (RHC) admitted for HF, post-HTx monitoring, or LVAD hemodynamic testing. PVP was transduced from an antecubital or more distal peripheral intravenous (IV) catheter site using a miniature digital, disposable pressure transducer (Centurion Compass Universal HG, Medline). Pressures were compared using Pearson’s correlation coefficient.
Results: 99 patients were enrolled with a mean age of 62 ± 12 years and a mean ejection fraction (EF) of 41 ± 21%. 74% of the patients had heart failure, 17% were HTx patients, and 9% were LVAD patients. The PVP measured with the novel pressure transducer was found to be highly correlated to CVP measured by RHC (r=0.80, p < 0.0001) (Figure). High correlation was also noted when broken down by HF (r=0.77, p < 0.0001), HTx (r=0.95, p < 0.0001), and LVAD groups (r=0.90, p < 0.0003). There was a high degree of correlation for HF patients with EF < 50% (r=0.74, p < 0.0001) and EF > 50% (r=0.90, p < 0.0001). A high degree of correlation was found for all peripheral IV insertion sites: antecubital (r=0.86, p=0.000071), forearm (r=0.76, p<0.00001), and hand (r=0.84, p<0.00001).
Conclusions: There is a high degree of correlation between PVP measured by a novel pressure transducer and CVP in HF, HTx, and LVAD patients. PVP measurements using this transducer are a reliable estimate of volume status in these patient populations.