Abstract 13033: Usefulness of MR-Derived Left Ventricular Global Longitudinal Strain and Left Atrial Strain to Predict Cardiovascular Events in Patients With HFpEF
Masataka Katahira, Takatoyo Kiko, Keiichiro Endo, Ryo Yamakuni, Shiro Ishii, Akiomi Yoshihisa, Kenji Fukushima, Hiroshi Ito, Yasuchika Takeishi- Physiology (medical)
- Cardiology and Cardiovascular Medicine
Background: The aim of this study was to evaluate the prognostic value of left ventricular global longitudinal strain (LVGLS) and left atrial strain (LAS) obtained from magnetic resonance imaging (MRI) feature tracking in patients with heart failure with preserved ejection fraction (HFpEF).
Method: We retrospectively enrolled 150 patients with HFpEF who underwent cardiac MRI from 2015 to 2022. LVGLS and LAS were evaluated from cine mode MRI images. The end point was defined as a composite of all-cause death, myocardial infarction and hospitalization due to decompensated heart failure.
Results: At a follow-up of 4.3 ± 2.0 years, 27 events occurred. After dividing the patients into four groups by the median LVGLS and the median LAS, the event-free rate was significantly lowest in the group of LVGLS > -14.3% and LAS < 13.0% than any other groups (P =0.002). In the Cox proportional hazard analysis, LVGLS and LAS were independent predictors of cardiac adverse events in the patients with HFpEF.
Conclusion: The assessment of combined LVGLS and LAS was useful to evaluate risk stratification in the patients with heart failure with HFpEF.