A Three-Dimensional MOF Electrochemical Sensor Based on Zn4O(BDC)3/Acetylene Black for Sensitive Rapid Detection of Fluazinam Residues in Foods

Abstract

Fluazinam is a benzamide fungicide commonly used in agricultural production to prevent and control fungal-induced plant diseases. However, its residues in food products can pose potential health hazards. To address this issue, we have developed an electrochemical sensor based on a MOF-5/AB-modified glassy carbon electrode (GCE) for sensitive detection of fluazinam. In this work, a high-performance electrochemical sensor was fabricated via a simple composite strategy by combining AB, which possesses high electrical conductivity and superior electron transfer ability, with MOF-5, a material featuring a well-developed porous structure and large specific surface area. The structural and morphological characteristics of the MOF-5/AB and electrochemical sensing performance toward fluazinam of MOF-5/AB/GCE are investigated. The MOF-5/AB/GCE exhibited outstanding electrochemical sensing performance for fluazinam detection, providing an ultralow detection limit of 0.0166 μM, a wide linear range of 0–100 μM, high sensitivity, excellent reproducibility and stability, and remarkable selectivity against common interfering species. In real samples, fluazinam yielded high recovery rates, confirming the potential of MOF-5/AB/GCE for practical environmental and biomedical monitoring applications. This research provides a novel and efficient sensing platform for electrochemical detection of fluazinam residues and offers a valuable reference for modification of MOFs and their extended applications in the field of electrochemical sensing.