DOI: 10.1097/rlu.0000000000006720 ISSN: 0363-9762

A Tale of 3 Tracers

Xiang Si, Yanfeng Xu, Keyu Zhang, Lingling Zheng, Jigang Yang

A 5-year-old boy underwent 18 F-FDG PET/CT before the histopathologic diagnosis of neuroblastoma, revealing a metabolically active left adrenal primary tumor with metastases to the liver. Following resection and chemotherapy, sequential 68 Ga-DOTATATE PET/CT and 18 F-MFBG demonstrated tracer-specific uptake patterns: 18 F-MFBG identified a solitary hepatic metastasis undetected by 68 Ga-DOTATATE. This case underscores the complementary diagnostic value of multimodal molecular imaging in pediatric neuroblastoma response assessment.

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