DOI: 10.1093/qjmed/hcad069.535 ISSN:

A Systematic Review for Cervical Intervertebral Disc Arthroplasty versus Anterior Cervical Discectomy and Fusion in the Treatment of Cervical Degenerative Spine Disorders

Amr Mohammed Nageeb El-Shahaby, Salah Mostafa Hamada, Abd-Elrahman Mohammed Hesham El-Gayar, Mohammed Ismaeil Ali
  • General Medicine


Cervical disc arthroplasty (CDA) is an increasingly accepted procedure for the treatment of symptomatic cervical degenerative disc disease. Multiple Level I evidence clinical trials have established cervical TDR to be a safe and effective procedure in the short-term.

Aim of the Study

is to provide a long-term assessment of cervical disc arthroplasty (CDA) versus anterior discectomy and fusion (ACDF) for the treatment of one- and two-level disc disease.

Patients and Methods

Systematic review of published English literature, the study was done from July 2014 to June 2020 and the study setting was Internet search through MEDLINE and Cochrane Collaboration Library.


Our study provided further evidence that CDA is superior in achieving long-term clinical outcomes such as overall success, NDI success and neurological success, VAS neck pain and arm pain, symptomatic ASD, total secondary surgery, and secondary surgery at the index level and at the adjacent level.


However, no clear benefit could be identified in regard to NDI score, total reported AE, serious AE, device/surgery- related AE, and radiological superior and inferior ASD. Welldesigned worldwide RCT with long-term follow up are still necessary for further evaluation in the future.

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