DOI: 10.1039/d6sc03610d ISSN: 2041-6520

A spatially confined “double-key lock” smart DNA hydrogel for dynamic detection of MicroRNA in cells

Liyun Shi, Dandan Liang, Jingyu Kuang, Yuting He, Dongyang Wang, Jiayi Shan, Ziyang Wang, Wei Shen, Hian Kee Lee, Sheng Tang

A spatially confined “double-key lock” smart DNA hydrogel integrating temperature responsiveness and target recognition was developed to realize dynamic monitoring of miRNA in cells.

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