A Rare Case Report of Type II Kounis Syndrome With Literature Review: Acute Anterior ST Elevation Myocardial Infarction Following Bee Sting

ABSTRACT

Kounis syndrome (KS), also known as allergic angina, is a rare but serious condition defined by acute coronary syndrome occurring alongside a hypersensitivity reaction. We report the case of a 42‐year‐old male smoker who developed Type II KS after a hymenoptera sting. The patient came to the emergency department with a sudden decreased level of consciousness and retrosternal chest pain. Electrocardiography showed ST‐segment elevation in the anterior leads, and coronary angiography revealed total proximal left anterior descending artery occlusion. Primary percutaneous coronary intervention (PCI) was performed successfully. Echocardiography documented a left ventricular ejection fraction (LVEF) of 35% with regional wall motion abnormalities, indicating significant myocardial injury. The patient was discharged with a treatment plan that included valsartan, spironolactone, bisoprolol, ticagrelor, acetylsalicylic acid, and atorvastatin. This case highlights the diagnostic and treatment challenges of KS and stresses the need for early recognition and a team‐based approach to achieve better clinical results.