DOI: 10.1002/ccr3.8656 ISSN: 2050-0904

A rare case of chikungunya encephalitis and its management: A case report and literature review

Pugazhendi Inban, Sai Harini Chandrasekaran, Preeti Kumari Yadav, Roshini Vijayakumar, Zenia Elavia, Mansi Singh
  • General Medicine

Key Clinical Message

Chikungunya encephalitis, though rare, warrants clinical attention due to its severe complications. Early identification and appropriate management are crucial for improved outcomes in patients with this rare manifestation of chikungunya virus (CHIKV) infection.


CHIKV infection is commonly associated with fever and joint pains, but neurological complications such as encephalitis are rare. Here, we present a unique case of confirmed chikungunya encephalitis in a 12‐year‐old male exhibiting atypical neurological symptoms. The diagnostic journey involved comprehensive neuroimaging and serological investigations, revealing intriguing findings on magnetic resonance imaging and positive CHIKV RNA in serum and cerebrospinal fluid. We discuss the clinical presentation, radiological characteristics, and management strategies, emphasizing the importance of recognizing this uncommon neurological manifestation of CHIKV infection.

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