DOI: 10.36106/ijar/9301204 ISSN:

A PROSPECTIVE STUDY ON ETIOLOGICAL PROFILE AND PATTERN OF DRUG RESISTANCE BY UROPATHOGENS ISOLATED FROM A TERTIARY CARE HOSPITAL IN WAYANAD

N V Sana Nazar, Deepthy B J, Ashwiny P, Soorya C.S
  • General Medicine
  • General Medicine
  • General Engineering
  • General Medicine
  • General Chemistry
  • Pulmonary and Respiratory Medicine
  • Pediatrics, Perinatology, and Child Health
  • Applied Mathematics
  • General Mathematics
  • Microbiology
  • Computer Science Applications
  • History
  • Education
  • General Medicine
  • Immunology

Introduction: Urinary Tract Infection is a spectrum of diseases caused by microbial invasion of the urinary tract that extends from the renal cortex of the kidney to the urethral meatus. These are primarily caused by bacteria, mostly Gramnegative organisms from the family Enterobacteriaceae, which can infect regardless of age. The aim of this study was to nd out the most prevalent bacteria causing UTI and the most vulnerable age group with UTI and also to identify the percentage of Community-acquired and Hospital-acquired UTIs. The study was conducted at the Microbiology Department Materials and Methods: of Dr. Moopens Medical College, Wayanad, Kerala, over a period of 3 months. All the urine samples obtained from patients to diagnose UTI were processed for identication by culture, morphological and biochemical tests. Antibiotic sensitivity was performed using Kirby- Bauer disc diffusion using standard and conrmatory method as per CLSI guidelines. Out of 722 samples cultured for isolating Results: the bacteria, 212 (29.4%) samples showed signicant growth of organisms. The major isolates identied were 99 E.coli (46.6%), 28 Klebsiella species (13.2%), 16 Enterococcus spp., (7.5%), and 14 Pseudomonas aeroginosa (6.6%). Among 212 samples with signicant growth, 153 (72.2%) were Hospital-acquired infections, and 59 (27.8%) were Community-acquired infections. Out of 212 samples with signicant growth, 153(72.2%) were hospital-acquired infections and 59 (27.8%) were community-acquired infections. Escherichia coli was found Conclusion: to be the most prevalent uropathogens followed by Klebsiella species. These organisms displayed high-level antimicrobial resistance. For preventing the spread of antimicrobial resistance it is important to plan antibiotic policies. This will also help to decrease the aimless use of antibiotics thereby prevent the further development of antimicrobial resistanc

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