DOI: 10.1039/d6ra01858k ISSN: 2046-2069
A plug-and-play multi-organ-on-chip for studying interaction between central nervous system and peripheral monocytes following neuroinjury from radiation and Parkinson's disease
Yu Chen, Zhirong Wan, Beiqin Liu, Hong Ma, Shuyue Wang, Yaoyuan Cui, Yulin Deng, Jichen DuA plug-and-play multi-organ-chip (PPMOC) with interconnected CNS insert and monocyte insert mimics CNS-monocyte interaction, where monocyte activation is induced by γ-ray neuroinjury or Parkinson's disease.