DOI: 10.1093/ofid/ofag690 ISSN: 2328-8957

A Pilot Study of Linezolid for Early Syphilis Treatment

Ryan M Nguyen, Chrysovalantis Stafylis, Kelika A Konda, E Michael Reyes-Diaz, Kori Keith, Keith Stokes, Catherine Creticos, Candice J McNeil, Philip A Chan, James B Brock, Byron Buck, Ebony Warren, Rica M Abbott, Jennifer L Nall, Peter Salhaney, Takila Keys, Jeffrey D Klausner

Abstract

In a study of oral linezolid among 18 patients with early syphilis, fifteen showed adequate serological response by six months. Among six patients treated with benzathine penicillin G, five showed adequate serological response. There were no serious adverse events. Linezolid shows promise for the treatment of early syphilis.

More from our Archive