Denis V. Barclay, Joaquina Gil‐Ramos, José O. Mora, Henri Dirren

A Packaged Rice‐Based Oral Rehydration Solution for Acute Diarrhea

  • Gastroenterology
  • Pediatrics, Perinatology and Child Health
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Summary: In a 12‐month community study in Ecuadorian preschool children, we compared a packaged rice‐based oral rehydration solution (R‐ORS) that contained 160 g of rice flour and 12 g of sucrose per liter as well as electrolytes and α‐amylase, and required cooking before consumption, to the standard glucose‐electrolyte oral rehydration solution (G‐ORS) for the treatment of acute non‐cholera diarrhea. The reconstituted R‐ORS had energy and protein contents of 620 kcal/L and 12g/L, respectively, and an osmolarity of 230 mosm/L. In all, 156 cases were treated with the R‐ORS and 144 with the standard G‐ORS. Cases treated with R‐ORS had a significantly shorter duration of diarrhea (p < 0.0001; median; 34 h versus 48 h), a lower number of stools (p < 0.001; median; four versus seven), and a greater weight gain after 4 days of treatment (p < 0.05; mean; 1.6% versus‐0.2%) than those treated with G‐ORS. ORS and total liquid intakes tended to be higher with the R‐ORS. The two ORS were equivalent for the correction of mild dehydration and the maintenance of normal hydration status.

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