Jiaxi Ru, Weiyuan Xu, Manchang Kou, Hu Dong, Xiaoliang Tang, Yu Chen, Lingling Kang, Lixiong Dai, Chao Liang

A novel Gd3+ DTPA-bisamide complex with high relaxivity as an MRI contrast agent

  • General Materials Science
  • Biomedical Engineering
  • General Chemistry
  • General Medicine

A novel Gd(iii) complex-based MRI contrast agent GdL has been designed and synthesized, which exhibited a much higher relaxivity than the commercially used Magnevist®, good water solubility, excellent stability, high biosafety and biocompatibility.

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