DOI: 10.1039/d6bm00251j ISSN: 2047-4830
A NIR assisted composite scaffold incorporating CuHP and melatonin for enhanced anti-infection and bone regeneration in an acute rat model of infected bone defect
Long Zhou, Shuangjian He, Jian Gu, Yunfei Liu, Peng ZhangA NIR-assisted PGCuM scaffold integrating CuHP and MT was fabricated. In infected rat bone defects, PGCuM + NIR achieved superior bacterial clearance and new bone formation. MT presence correlated with inflammation resolution and M2 polarization.