DOI: 10.1039/d4sc00595c ISSN: 2041-6520
A near-IR ratiometric fluorescent probe for the precise tracking of senescence: a multidimensional sensing assay of biomarkers in cell senescence pathways
Haihong Liu, Ruidian Lv, Fuxiang Song, Yaqun Yang, Fei Zhang, Liantao Xin, Peng Zhang, Qian Zhang, Caifeng Ding- General Chemistry
A NIR fluorescent probe for monitoring senescence was developed with SA-β-gal and HClO as targets under high lysosomal pH conditions. The precise tracking of cellular/in vivo senescence was achieved with a ratiometric sensing pattern.