DOI: 10.1039/d6tb01073c ISSN: 2050-750X
A mitochondria targeting aggregation-induced emission phototheranostic agent for photodynamic synergistic therapy of triple-negative breast cancer
Xinhui Zhai, Yifan Liu, Yazixuan Feng, Jingwen Dai, Zhaorui Song, Wenna Hou, Yining Zhang, Chuhan Ma, Jin PeiFormulated with an AIE photosensitizer, TMP, and an immunostimulant, CpG, DTC NPs enable mitochondria-targeted PDT/immunotherapy, synergizing with paclitaxel to suppress TNBC via ICD and T-cell activation.