DOI: 10.1039/d3cc02771f ISSN:
A genetically encodable and fluorogenic photo-crosslinker via photo-induced defluorination acyl fluoride exchange
Jielin Fu, Sitong Li, Lijun Deng, Xiaohu Zhao, Zhipeng Yu- Materials Chemistry
- Metals and Alloys
- Surfaces, Coatings and Films
- General Chemistry
- Ceramics and Composites
- Electronic, Optical and Magnetic Materials
- Catalysis
m-TFMAK was developed as a fluorogenic photo-crosslinker, incorporated into proteins via genetic code expansion in living cells. Photo-DAFEx of the encoded m-TFMAK allows proteomic tracking and visualization of protein–protein interactions.