A double rare earth doped CD nanoplatform for nanocatalytic/starving-like synergistic therapy with GSH-depletion and enhanced reactive oxygen species generation

doi:10.1039/d3tb00959a

Shufeng Cui, Bin Wang, Changyu Zhai, Shanshan Wei, Hongyuan Zhang, Guoying Sun

A double rare earth doped CD nanoplatform for nanocatalytic/starving-like synergistic therapy with GSH-depletion and enhanced reactive oxygen species generation

General Materials Science
Biomedical Engineering
General Chemistry
General Medicine

Ce–Gd@CDs–GOx can promote generation of ˙OH and oxidation of glucose, achieving nanocatalytic anticancer activities and starving-like synergistic therapy. Ce ions can decompose H2O2 to relieve hypoxia and deplete GSH, for precise treatment using T1-weighted MR imaging.

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A double rare earth doped CD nanoplatform for nanocatalytic/starving-like synergistic therapy with GSH-depletion and enhanced reactive oxygen species generation

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A double rare earth doped CD nanoplatform for nanocatalytic/starving-like synergistic therapy with GSH-depletion and enhanced reactive oxygen species generation

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