DOI: 10.36106/ijar/8304486 ISSN:

A CROSS-SECTIONAL STUDY COMPARING PAP SMEAR AND COLPOSCOPY IN DETECTION OF PREMALIGNANT LESION OF CERVIX

Sweta Pathak, Nayan Chandra Sarkar, Manidip Pal, Anindita Jana
  • General Medicine
  • Pharmacology (medical)
  • Complementary and alternative medicine
  • Pharmaceutical Science
  • Materials Chemistry
  • Economics and Econometrics
  • Media Technology
  • Forestry
  • General Medicine
  • General Medicine
  • General Engineering
  • General Medicine
  • Applied Mathematics
  • General Mathematics
  • Pulmonary and Respiratory Medicine
  • Pediatrics, Perinatology, and Child Health
  • General Medicine
  • General Chemistry

Introduction – Cervical cancer is one of the leading cause of cancer mortality, accounting for 17% of all cancer deaths among women of 30-69 years age. As sustaining with high-quality cytology based Pap smear programs are difcult in low-resource settings of India, screening efforts should be directed towards cost-effective strategies that are more affordable and quality-assured. Aim - Materials to identify better screening method of premalignant cervical lesion in sexually active women using Pap smear and Colposcopy. And Methods – cross-sectional study upon 100 women of 21-65 years age attending GOPD at tertiary medical center of West Bengal with C/O irregular bleeding p/v, white discharge, post-coital bleeding, dyspareunia. Pap smear and colposcopy done for all of them. PAP smear is Results – abnormal for 6.1% cases and colposcopy is abnormal in 7.6% cases. Association of Pap smear and colposcopy has been found as statistically signicant. The association of biopsy and PAP report found as statistically insignicant. In all CIN cases, biopsy become abnormal. Statistical analysis revealed that colposcopy has a sensitivity of 83.3, specicity: 100.0, PPV : 100.0, NPV: 98.4 and accuracy of 98.48% . Pap smear has sensitivity 66.7, Specicity: 100.0, Positive Predictive Value: 100.0, Negative Predictive Value: 96.8 and Accuracy: 96.96%. Conclusion – Colposcopy has been found to have better sensitivity than Pap smear as a screening method for CIN and micro-invasive CA cervix to decrease the disease specic morbidity and mortality in India.

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