A CROSS-SECTIONAL STUDY COMPARING PAP SMEAR AND COLPOSCOPY IN DETECTION OF PREMALIGNANT LESION OF CERVIX
Sweta Pathak, Nayan Chandra Sarkar, Manidip Pal, Anindita Jana- General Medicine
- Pharmacology (medical)
- Complementary and alternative medicine
- Pharmaceutical Science
- Materials Chemistry
- Economics and Econometrics
- Media Technology
- Forestry
- General Medicine
- General Medicine
- General Engineering
- General Medicine
- Applied Mathematics
- General Mathematics
- Pulmonary and Respiratory Medicine
- Pediatrics, Perinatology, and Child Health
- General Medicine
- General Chemistry
Introduction – Cervical cancer is one of the leading cause of cancer mortality, accounting for 17% of all cancer deaths among women of 30-69 years age. As sustaining with high-quality cytology based Pap smear programs are difcult in low-resource settings of India, screening efforts should be directed towards cost-effective strategies that are more affordable and quality-assured. Aim - Materials to identify better screening method of premalignant cervical lesion in sexually active women using Pap smear and Colposcopy. And Methods – cross-sectional study upon 100 women of 21-65 years age attending GOPD at tertiary medical center of West Bengal with C/O irregular bleeding p/v, white discharge, post-coital bleeding, dyspareunia. Pap smear and colposcopy done for all of them. PAP smear is Results – abnormal for 6.1% cases and colposcopy is abnormal in 7.6% cases. Association of Pap smear and colposcopy has been found as statistically signicant. The association of biopsy and PAP report found as statistically insignicant. In all CIN cases, biopsy become abnormal. Statistical analysis revealed that colposcopy has a sensitivity of 83.3, specicity: 100.0, PPV : 100.0, NPV: 98.4 and accuracy of 98.48% . Pap smear has sensitivity 66.7, Specicity: 100.0, Positive Predictive Value: 100.0, Negative Predictive Value: 96.8 and Accuracy: 96.96%. Conclusion – Colposcopy has been found to have better sensitivity than Pap smear as a screening method for CIN and micro-invasive CA cervix to decrease the disease specic morbidity and mortality in India.