A Comparison of Ovine-Reinforced Hybrid Mesh (OviTex® PRS) With Porcine Acellular Dermal Matrix (STRATTICE™) in the Treatment of Advanced Breast Implant Capsular Contracture
Cyril J Harfouche, Michael J Brucker, Salvatore J PacellaAbstract
Background
Tissue reinforcement techniques with porcine acellular dermal matrices have been widely adopted as standard care in treating capsular contracture. However, the application of alternative xenograft or mesh materials has not been widely studied.
Objectives
To examine the efficacy of OviTex® PRS Reinforced Tissue Matrix (Resorbable) (Tela Bio, Malvern, PA), a hybrid ovine-reinforced mesh, in comparison to STRATTICE™ Reconstructive Tissue Matrix (Allergan, Irvine, CA), in patients with advanced capsular contracture.
Methods
A retrospective review was conducted on patients who underwent breast revision surgery for Baker grade III or IV capsular contracture. Patient data was reviewed for outcomes, complications, cost and post-operative incidence of recurrent capsular contracture after treatment with each specific mesh.
Results
59 of 89 breasts (66.3%) were treated with OviTex® and 30(33.7%) were treated with STRATTICE™. All patients experienced a reduction in Baker grades. In patients treated with OviTex®, 96.6% (n=57) of breasts had a post-operative Baker grade I with the remaining 3.4% (n=2) breasts presenting with a Baker grade II. In comparison, 73.3% (n=22), 23.3%(n=7) and 3.3%(n=1) of the STRATTICE™ cohort presented with Baker Grades I, II and III, respectively. This demonstrated a statistically significant improvement in Baker grade capsular contracture in the OviTex® cohort (p<0.05) compared to STRATTICE™. Average cost was $27.37/cm2 for STRATTICE™compared to $22.28/cm2 for OviTex® PRS.
Conclusions
OviTex® may be successfully utilized to treat capsular contracture. Patient outcomes may be superior to STRATTICE™ in recurrent capsular contracture, particularly when a previous acellular dermal matrix had been utilized. Cost data shows improved savings with the use of OviTex® compared to STRATTICE™.