A COMPARATIVE STUDY OF METABOLIC SYNDROME AMONG DIABETIC AND NON-DIABETIC PATIENTS IN A TERTIARY CARE HOSPITAL

Background: Relationship of diabetes with metabolic syndrome is often temporal in nature as diabetes is not only one of the component factors of metabolic syndrome but it is also a metabolic disorder that increases the risk of metabolic syndrome too. The risk of Type 2 Diabetes mellitus has been shown to rise markedly with increase in degree of obesity. Aim: The present study was conducted to compare the incidence of metabolic syndrome in diabetic and non-diabetic subjects. Materials and Method: Acase control study was conducted among 100 patients(50cases and 50 control) at MIMS, Uttar Pradesh for the period of January 2021 to December 2022. Upon obtaining informed consent, demographic information, history taking, general and systemic examination, anthropometric data, blood pressure measurements, fasting and post prandial blood sugar, HbA , blood urea, serum creatinine, triglyceride, low density lipoprotein and HDLassessment done.Inclusion of anthropometry matched cases led 1c to matching of two groups for certain metabolic syndrome risk factors like central obesity. Results: Study suggestive of higher incidence of metabolic syndrome in diabetic patients(80%) compared to non diabetic patients(38%). Signicantly higher proportion of cases as compared to controls had history of dyslipidaemia(case=58%,control=6%) and respiratory disease(case=6%,control=0%). Mean BMI of cases(62%) was signicantly higher as compared to that of controls(26%). Cases as compared to controls had signicantly higher triglyceride and signicantly lower HDL levels. Incidence of low HDL levels and insulin resistance was signicantly higher in cases as compared to that of controls. Conclusion: Incidence of metabolic syndrome was found to be higher in diabetic patient compared to non diabetic patients which was statistically signicant.