DOI: 10.1039/d3cs00518f ISSN: 0306-0012
A closer look at amyloid ligands, and what they tell us about protein aggregates
Timothy S. Chisholm, Christopher A. Hunter- General Chemistry
A database of over 2000 different ligands that bind amyloid fibrils (Aβ, tau, or αSyn) has been compiled and used to investigate the factors that influence binding affinity and selectivity.