A CASE OF PIGMENTED NEUROFIBROMA WITH HYPERTRICHOSIS

This study explores the uncommon overlap of neurobromas and hypertrichosis. Neurobromas, benign tumors from nerve tissue, occasionally exhibit melanin-rich pigmented cells, a rarity in clinical cases. Hypertrichosis, marked by excessive hair growth in non-androgen-dependent regions, is another central theme. The coexistence of these conditions is rarely seen in clinical practice. We detail an unusual case of a 22-year-old male with hyperpigmented macules, nodules, and hypertrichosis on his trunk. While signs hinted at neurobromatosis type 1 (NF1), the lack of standard criteria complicated diagnosis. Key observations included Lisch nodules, absence of typical neurobromas, and no family history of similar skin conditions. MRI scans negated malignancies. The patient's examination revealed extensive terminal hair growth and subcutaneous anomalies. The discussion sheds light on hypertrichosis, its potential origins, and its link with neurobromas, especially around the periorbital area. The study emphasizes the importance of thorough clinical evaluations for unconventional tumor presentations and delves into the mechanisms behind hypertrichosis. Conclusively, the research points to emerging treatments for hypertrichosis, with lasers and chemical agents leading the way.