Outline
DOI: 10.1039/d6tb02388f ISSN: 2050-750X
A bioorthogonal capture-and-release platform for isolation of nanoparticle protein coronas
Yaxin Zhou, Yinuo Sun, Xiaochun Sun, Haiping Zhong, Tao Liu, Kun Ge, Yachao Tian, Guohua Liu, Yi-Feng Wang, Jinchao Zhang, Shutao GuoA bioorthogonal capture–release platform enables in situ protein corona formation on immobilized nanoparticles, followed by mild light-triggered recovery. The 24-well format supports parallel processing and downstream proteomic analysis.
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