Serena Y. Kuang

A better explanation of countercurrent multiplication in the formation of the corticopapillary osmotic gradient in the outer medulla

  • General Medicine
  • Physiology
  • Education

Countercurrent multiplication is widely accepted as the mechanism for the generation of the corticopapillary osmotic gradient in the outer medulla of mammalian kidneys, but the current explanations of it in textbooks and the literature are inefficient and incomplete, leading to confusion for students. This article shares a modified version of countercurrent multiplication with more understandable explanation as a way of motivating peer discussion, further improvement, and future research.

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