72242 - Laparoscopy for impalpable undescended testis – do children with syndromes have worse outcome?
Agnes Raaschou Byström, Caroline Ericsson Selin, Nilla Hallabro, Martin SalöAbstract
Introduction
Few studies describe the outcome after laparoscopy for impalpable undescended testis (UDT) in children with syndromes. Thus, the aim of the study was to evaluate final diagnosis and outcome after laparoscopy for impalpable UDT with comparison of children with and without a defined syndrome.
Method
An ethically approved retrospective study of boys who underwent laparoscopy for impalpable UDT between 2018 - 2022 was conducted. Variables between children with and without a syndrome were compared using univariate analysis. A syndrome was defined as caused by a chromosomal abnormality or a mutation/genetic polymorphism in a specific gene locus with previously known connected comorbidities/malformations.
Result
A total of 298 boys who underwent laparoscopy for impalpable UDT were included. The median age was 14 months and 32 (10.7%) had a syndrome. Boys with syndromes were significantly older and more often had bilateral disease. Overall, intraabdominal UDT was found in 42%, a testicular nubbin in 22%, vanishing testis in 23% and other miscellaneous findings in the rest. Abdominal UDT was more common in boys with syndrome (66 % vs 39%, p<0.01) and findings of a testicular nubbin was more common in boys without a syndrome (24% vs 3%, p<0,01). Of all boys with completed follow-up after FS2, the atrophy rate was 18% and the re-ascent rate 4%, without differences between boys with and without a syndrome.
Discussion
Boys with syndromes and impalpable UDT have higher rate of true UDT and lower rate of testicular nubbin at time of laparoscopy, but not worse outcome after completed FS2.