3D Bioprinting of Nanocellulose Scaffolds for Tissue Engineering Applications
Nur Izzah Md Fadilah, Rio Yamagishi, Andik Nisa Zahra Zainuddin, Nurul Nadhirah Mustakim, Farah Alea Rosemanzailani, Mh Busra FauziNanocellulose has remarkable mechanical qualities, sustainability, and biocompatibility. It is produced from renewable resources, like bacteria or wood. This chapter explores the use of nanocellulose as a component of bioink, emphasising its capacity to replicate the structure of the extracellular matrix and facilitate the development and differentiation of cells. Complex three-dimensional tissue constructions with customised topologies can be created by layer-by-layer deposition of nanocellulose bioinks using sophisticated bioprinting techniques, such as extrusion-based or inkjet-based approaches. These bioprinted scaffolds have a lot of potential for use in wound healing, organ regeneration, and disease modelling in regenerative medicine. Furthermore, the ecologically favourable properties of nanocellulose correspond with the increasing need for sustainable biomedical materials. The incorporation of nanocellulose into bioprinted scaffolds holds great potential to transform tissue engineering through sustainable, biocompatible, and adaptable approaches to tissue regeneration and repair, provided that research in this field advances.