DOI: 10.1002/chem.202301898 ISSN: 0947-6539
2H‐Phosphindole‐Enabled Dearomatization and [4+2] Cycloaddition of (Hetero)Arenes
Haotian Luo, Junjian Wang, Rongqiang Tian, Zheng Duan- General Chemistry
- Catalysis
- Organic Chemistry
Abstract
The heavier main group multiple bonds offer an effective tool for small molecule activation. Transient 2H‐phosphinidole working as a reactive phosphadiene system undergoes phospha‐Diels‐Alder reaction with a wide range of non‐activated aromatic carbocycles and heterocycles, including naphthalene, anthracene, phenanthrene, furan, thiophene, pyrrole, pyridine, and benzo‐fused heterocycles, affording concise access to a range of polycyclic fused rings feature with phosphorus at the bridgehead. These results demonstrate that non‐activated (hetero)arenes are capable of acting as 2π systems in [4+2] cycloaddition with highly reactive 2H‐phosphindole complex.