DOI: 10.1039/d6dt01481j ISSN: 1477-9226
2D and 3D antiproliferative properties of Schiff base and reduced Schiff base palladium(
ii
) complexes in doxorubicin-resistant colorectal cancer cells
Hadi Amiri Rudbari, Kimia Forooghi, Zahra Kazemi, Beatriz Salas, Mehdi Sahihi, José V. Cuevas-Vicario, Sandra Cordeiro, Ruben Valente, Pedro V. Baptista, Olivier Blacque, Alexandra R. Fernandes Three halogenated Pd(
ii
) complexes were synthesized and characterized spectroscopically, crystallographically, and computationally, then evaluated for DNA binding and anticancer activity in 2D/3D models of doxorubicin-resistant colorectal cancer.