DOI: 10.1039/d6ra06492b ISSN: 2046-2069

1,2,3-Triazole-linked DNA biosensors: molecular design to real-time applications

Gaurav Bhatoe, Nancy George, Gurjaspreet Singh, Anshu, Jandeep Singh

This review highlights CuAAC in DNA biosensing, using 1,2,3-triazole for linkage, surface and dual-strand modification, integrated with nanomaterials, DNA structures, DNAzymes, CRISPR and ATRP for signal amplification and precise detection.