DOI: 10.66106/lyyaa3.20260303 ISSN: 3105-675X

基层卫生中心高血压合并 2 型糖尿病患者服药依从性现状及影响因素研究

胡俊瑶 Junyao Hu
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Abstract：Objective：To understand the current status of medication compliance in patients with hypertension and type 2 diabetes in primary health centers，and to explore the influencing factors from the aspects of social demographic characteristics，disease-related factors，medication regimens and social support，so as to provide evidence-based basis for chronic disease management in primary health centers.Methods：From June 2025 to March 2026，a total of 420 patients with hypertension and type 2 diabetes in a community health service center in Chengdu City，Sichuan Province were selected as the research objects by convenience sampling method.The general information questionnaire and the Chinese version of the 8-item Morisky Medication Adherence Scale （MMAS-8） were used for the questionnaire survey.Univariate analysis and multivariate Logistic regression analysis were used to screen the influencing factors of medication compliance.Results：The score of medication compliance of 420 patients was （5.52±1.12），and 172 patients （40.95%）had high medication compliance.Multivariate logistic regression analysis showed that age ≥65 years old （OR=0.521，95%CI：0.336-0.807），the types of daily medication ≥3 （OR=0.358，95%CI：0.228-0.562），the frequency of daily medication ≥3 （OR=0.442，P < 0.05），and the frequency of daily medication ≥3 （OR=0.442，P < 0.05）were independent risk factors for adverse events.Urban employee medical insurance （OR=2.013，95%CI：1.278-3.171），receiving medication guidance （OR=1.872，95%CI：1.203-2.914），higher level of social support （OR=1.965，95%CI：1.261-0.748）were risk factors for medication compliance.95%CI：1.241-3.112）were the protective factors of medication compliance （all P&lt；0.05）.Conclusion ：The overall medication compliance of patients with hypertension and type 2 diabetes in primary health centers is low.Old age，≥3 kinds of daily medication，and ≥3 times of daily medication were the main barriers to poor compliance，while urban employee medical insurance，medication guidance and good social support could significantly improve compliance.Primary health centers should carry out precise and individualized intervention measures according to the above factors.

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