DOI: 10.1111/pde.15828 ISSN: 0736-8046
Rapidly Progressive Idiopathic Pyoderma Gangrenosum in a Pediatric Patient Successfully Treated With Infliximab
Nikhita J. Perry, Stephanie Wang, Robert Smith, Robert Duffy, Maria Queenan, Marissa J. Perman, Melissa A. Lerman, Mary LarijaniABSTRACT
Pyoderma gangrenosum (PG) is a rare skin disorder with poorly understood pathophysiology. PG infrequently occurs in children, and approximately 4% of patients with PG are infants and children. First line therapy is topical and systemic corticosteroids, which typically yields rapid response. We report a case of rapidly progressive pediatric PG of unknown inciting cause that ultimately required multi‐modal therapy with systemic and topical corticosteroids, high‐dose infliximab, and colchicine.