DOI: 10.1039/d3sc03342b ISSN:

Kinetics of ligand exchange in solution: a quantitative mass spectrometry approach

Quentin Duez, Paul Tinnemans, Johannes A. A. W. Elemans, Jana Roithová
  • General Chemistry

Delayed reactant labelling can provide thermodynamic parameters (ΔG, ΔH, and ΔS) of solution equilibria using ESI-MS monitoring. As a proof of concept, we investigated the equilibria of pyridine ligands with macrocyclic porphyrin cage complexes.

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