DOI: 10.1039/d3tb01094e ISSN:

Glutathione-sensitive mesoporous nanoparticles loaded with cinnamaldehyde for chemodynamic and immunological therapy of cancer

Lichong Zhu, Wenyue Li, Chuang Liu, Saisai Yue, Yuanyuan Qiao, Yingying Cui, Junwei Cheng, Ming Zhang, Peisen Zhang, Beibei Zhang, Yi Hou
  • General Materials Science
  • Biomedical Engineering
  • General Chemistry
  • General Medicine

We proposed a GSH-responsive mesoporous organosilica nanoparticles-based nanomedicine that can target tumor mitochondria. The nanomedicine can induce apoptosis and immunogenic death of tumor cells, realizing the chemodynamic and immunological therapy of cancer.

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