Evaluation of Dissolution of Pulp by Sodium Hypochlorite when Mixed with Tetrasodic Etidronate and Disodic Ethylenediamine Tetraacetate under Controlled Flow
Mukesh Kumar, Siddharth Shahi, Lalit Kumar Agarwal, Fahiem Mohammad Mohammad El-Shamy, Khushboo Gupta, Nidhi Aggarwal- General Pharmacology, Toxicology and Pharmaceutics
- General Biochemistry, Genetics and Molecular Biology
- Bioengineering
- General Pharmacology, Toxicology and Pharmaceutics
- General Biochemistry, Genetics and Molecular Biology
- Bioengineering
ABSTRACT
Background:
Sodium hypochlorite serves as the most efficient root canal irrigating fluid.
Objectives:
This study’s goal was to assess the replenished NaOCl’s capacity to dissolve the tissue of pulp when combined with 9% tetrasodic etidronate (Na4HEBP), 18% tetrasodic etidronate (Na4HEBP), and 17% disodic ethylenediaminetetraacetate (Na2EDTA) under continuous controlled administration.
Materials and Methods:
Hundred and twenty complete undamaged teeth of the anterior mandible extracted due to periodontal problems within forty-eight hours were taken as a source of the pulp tissue.
Results:
It was found that there was a decrease in the weight of pulp tissue in all groups except negative control.
Conclusion:
NaOCl’s potential to dissolve tissue with chelating agents like EDTA and HEBP inside the root canal was unaffected when there was controlled administration of EDTA and HEBP.